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...Overview southern blot dna digestion based hybridization cobra msp bisulfite sequencing real time methylight massarray pyrosequencing one of the older techniques for not as widely used any more due to development pcr and other cheap fast outdated but just employed process step use restriction enzymes cut electrophoresis separate fragments by size transfer from gel a membrane hybridize radiolabeled probe sample is washed remove extraneous radio probes advantages simple can detect multiple similar sequences well suited analyzing long stretches disadvantages requires large amount consuming labor intensive limited sensitivity interesting gif http www slic wsu edu hurlbert micro images southernblot...