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picture1_Pathophysiology Of Disease Pdf 115249 | 229390441


picture2_Pathophysiology Of Disease Pdf 115249 | 229390441 picture3_Pathophysiology Of Disease Pdf 115249 | 229390441

 82x       Filetype PDF       File size 0.25 MB       Source: core.ac.uk


File: Pathophysiology Of Disease Pdf 115249 | 229390441
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by The University of Sydney: Sydney eScholarship Journals online Orbit: The University of Sydney  ...

icon picture PDF Filetype PDF | Posted on 03 Oct 2022 | 2 years ago
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...View metadata citation and similar papers at core ac uk brought to you by provided the university of sydney escholarship journals online orbit undergraduate research journal pathophysiology krabbe disease aimee davenport peter williamson rosanne taylor faculty veterinary science is a rapidly progressive lysosomal storage disorder that primarily affects infants accumulation psychosine cytotoxic substrate in myelin forming cells results death these degeneration debris activates neuroinflammatory response which plays significant role pathogenesis this exact mechanisms causes cell pathogenic cascade are unknown twitcher mouse an animal model has been extensively utilized for pathophysiological there increasing evidence mode mediated apoptosis found activate secretory phospholipase cultured oligodendrocytes also reported up regulate stress activated protein kinase signaling transduction pathway down survival pathways more recent finding induces peroxisomal dysfunction brain review aims prov...
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