th b pharm 5 semester pharmacology ii bp503t unit iii autacoid the word autacoid comes from the greek autos self akos medicinal agent or remedy introduction histamine serotonin prostaglandins some ...
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...Th b pharm semester pharmacology ii bpt unit iii autacoid the word comes from greek autos self akos medicinal agent or remedy introduction histamine serotonin prostaglandins some vasoactive peptides belong to a group of compounds called autacoids they all have common feature being formed by tissues on which act so function as local hormones also differ circulating in that are produced many rather than specific endocrine glands types important include hydroxytryptamine ht leukotrienes and kinins beta aminoethyl imidazole is decarboxylation ring containing amino acid histidine basic amine stored mast cell basophil granules secreted when ca interact with membrane receptors antigen interacts fixed immunoglobulin e plays central role immediate hypersensitivity type allergic responses actions bronchial smooth muscle blood vessels account for symptoms response addition certain clinically useful drugs can directly cells release thereby explaining their untoward effects has major regulation gas...