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...I bo a n l c y t chauhan et al j anal bioanal tech e journal of hc la doi nruoj seuqi analytical bioanalytical techniques issn review article open access method development and validation concise ashish bharti mittu priyanka smpic niper mohali punjab india shikhar s sadan sr sec school dhampur bijnor abstract are the continuous inter dependent task associated with research quality control assurance departments procedures play critical role in equivalence risk assessment management it helps establishment product specific acceptance criteria stability results should demonstrate that procedure is suitable for its intented purpose design experiment powerful tool characterization professionals be comfortable to use characterize optimize an effective can provide significant improvements precision reduction bias errors further help avoid costly time consuming exercises keywords accuracy sop early used guide introduction life cycle brief as shown figure common steps followed follows standard a...