Outline • Introduction • Problem statement • Aim • Methodology • Conclusion • Future therapeutic agents • References 2 Introduction • The essential purpose of pharmaceutical drugs is to serve human beings by preventing diseases and enabling them to enjoy optimal health [1]. • In preventing these diseases, are challenges of multi-drug and antineoplastic resistances [2]. 3 Analytical instrumentation and analytical methods • In line with these diseases and their challenges, the role of analytical methods and analytical instrumentation in assessing drugs’ qualities in medicinal inorganic chemistry is important in order to make drugs serve their purpose [1]. 4 Administration ...
Medicinal chemistry A branch of chemistry which mainly deals with the design, development and synthesis of pharmaceutical drugs Objectiv e Classification of drugs Nomenclature of drugs Common diseases and their treatment by drugs Biological classification Chemical classification Commercial classification Nomenclature of drugs Analgesics Antipyretics Anesthetics Anti-inflammatory drugs Drugs affecting central nervous system Tranquilizers Sedatives Hypnotics ...
Learning objectives To understand the factors the contribute to a marketable antibiotic. To become familiarised with medicinal chemistry. To understand some of the approaches that have been used to design/improve antibiotics i.e. we are focusing on human ingenuity in drug discovery. Microbes have been making antibiotics for billions of years Previous lectures have focused on the fact that microbes are the masters of making antibacterial compounds. Driven by competition between microbes. Evolution of antibacterial properties. Human exploitation of these compounds for medicine. What properties does a good antibiotic have? From microbe’s point of view: Must restrict or prevent ...