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picture1_Chemistry Ppt 70490 | Bio8041 Lecture 8


picture2_Chemistry Ppt 70490 | Bio8041 Lecture 8 picture3_Chemistry Ppt 70490 | Bio8041 Lecture 8

 96x       Filetype PPTX       File size 2.81 MB       Source: teaching.ncl.ac.uk


File: Chemistry Ppt 70490 | Bio8041 Lecture 8
Learning objectives To understand the factors the contribute to a marketable antibiotic. To become familiarised with medicinal chemistry. To understand some of the approaches that have been used to design/improve ...

icon picture PPTX Filetype Power Point PPTX | Posted on 30 Aug 2022 | 2 years ago
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...Learning objectives to understand the factors contribute a marketable antibiotic become familiarised with medicinal chemistry some of approaches that have been used design improve antibiotics i e we are focusing on human ingenuity in drug discovery microbes making for billions years previous lectures focused fact masters antibacterial compounds driven by competition between evolution properties exploitation these medicine what does good from microbe s point view must restrict or prevent growth competitor be amenable self resistance mechanism other secondary such as regulation production pharma patentable administration preferably oral distributed infection site mass produced low cost chemically modifiable metabolised elimination non toxic and no breakdown products not same concerns an compound is necessarily going sense pharmacokinetics absorption distribution metabolism excretion toxicity adme t make decision hit lead based beginning long journey was golden age majority classes unique...
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