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picture1_Hplc Slideshare 68169 | Chem 30cl Lecture 5b Chiral Gc


picture2_Hplc Slideshare 68169 | Chem 30cl Lecture 5b Chiral Gc picture3_Hplc Slideshare 68169 | Chem 30cl Lecture 5b Chiral Gc

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File: Hplc Slideshare 68169 | Chem 30cl Lecture 5b Chiral Gc
Introduction • Chiral stationary phase are used in gas-liquid chromatography (GC/GLC) and liquid-solid chromatography (HPLC) • Chiral GC columns are frequently used in pharmaceutical research (i.e., enantiomeric purity of ...

icon picture PPTX Filetype Power Point PPTX | Posted on 28 Aug 2022 | 2 years ago

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...Introduction chiral stationary phase are used in gas liquid chromatography gc glc and solid hplc columns frequently pharmaceutical research i e enantiomeric purity of drugs quality control nature products forensics etc commonly phases amino acid derivatives chirasil val metal complexes l hydroxyproline cu carbohydrate cyclodextrins there three a form b g number glucose units centers external diameter pm internal volume cavity nm water solubility melting or decomposition point k oc ii the following interactions between an analyte cyclodextrin have influence on selectivity column inclusion which depends size substrate dipole functional groups involved separation hydrophobic is function carbon content hydrogen bonds depend capping steric different enantiomers diastereomers interact differently epoxide simulation low tech epoxides compound p pa styrene oxide phenylacetaldehyde alkene aldehyde ketone acetophenone c d retention time min for some major product elutes first minor afterwards ca...
								

							

						
	
												
				
					
					
					
			
					
				
				
		
	

	
		





	

	
				

						

						
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										Category:  Uncategorized / Uncategorized 
										
Posted on: 28 Aug 2022 | 2 years ago
										
										
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Filetype: PPTX
										
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