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picture1_Pro Sanjay Khattri Anti Rheumatoid Drugs


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File: Pro Sanjay Khattri Anti Rheumatoid Drugs
ANTIRHEUMATOID DRUGS Prof. Sanjay Khattri Dept. of Pharmacology & Therapeutics King George’s Medical University 1 RHEUMATOID ARTHRITIS (RA) • Rheumatoid arthritis (RA) is a chronic inflammatory disease of ...

icon picture PDF Filetype PDF | Posted on 17 Jan 2023 | 2 years ago

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...Antirheumatoid drugs prof sanjay khattri dept of pharmacology therapeutics king george s medical university rheumatoid arthritis ra is a chronic inflammatory disease unknown aetiology marked by symmetric peripheral polyarthritis the wrists metacarpophalangeal mcp and proximal interphalangeal pip joints stand out as most frequently involved may result in variety extraarticular manifestations including fatigue subcutaneous nodules lung involvement pericarditis neuropathy vasculitis hematologic abnormalities pathogenic mechanisms synovial inflammation from complex interplay genetic environmental immunologic factors that produces dysregulation immune system breakdown self tolerance associated with allelic variation hla drb gene which encodes mhc ii chain molecule preclinical stage characterized supported finding autoantibodies rf anti ccp cyclic citrullinated peptide antibodies be found sera pathologic hallmarks are proliferation focal bone erosions thinning articular cartilage...
								

							

						
	
												
				
					
					
					
			
					
				
				
		
	

	
		





	

	
				

						

						
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										Category:  Uncategorized / Uncategorized 
										
Posted on: 17 Jan 2023 | 2 years ago
										
										
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Filetype: PDF
										
File size: 0.85 MB
										
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