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...Mitra and tomar j genet eng biotechnol journal of genetic engineering https doi org s biotechnology review open access hybridoma technology advancements clinical significance future aspects sanchita pushpa chaudhary abstract background is one the most common methods used to produce monoclonal antibod ies in this process antibody producing b lymphocytes are isolated from mice after immunizing with specific antigen fused immortal myeloma cell lines form hybrid cells called these hybri doma cultured a lab antibodies against can be achieved by an vivo or vitro method it preferred above all available because thus produced high purity highly sensitive main body useful diagnostic imaging therapeutic purposes have very once become stable offer limitless production homogenized also cost effective targeted important tool various fields research such as toxi cology animal medicine pharmacology molecular biology extensively diagnosis applications radiolabeled probes detect tumor antigens living sy...