module fixation of tissues histology and cytology 5 notes fixation of tissues 5 1 introduction it is a process by which the cells or tissues are fixed in chemical and ...
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...Module fixation of tissues histology and cytology notes introduction it is a process by which the cells or are fixed in chemical partly physical state so that they can withstand subsequent treatment with various reagents minimal distortion morphology no decomposition objectives after reading this lesson you will be able to z aims explain principle describe properties factors affecting types preserve as close their living possible b prevent autolysis bacterial attack c from changing shape size during processing d harden e allow clear staining sections subsequently f improve optical differentiation results denaturation coagulation protein fixatives have property forming cross links between proteins thereby gel keeping everything vivo relation each other precipitation penetration rate differs different depending on molecular weight fixative ph satisfactory occurs outside range alteration structure cell may take place temperature room alright for at high there volume changes because membra...