introduction functional group pk the acidity of organic compounds is often determined a by neighboring groups because they can help stabilizing alkane 50 the resulting anion i e halogen nitro ...
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...Introduction functional group pk the acidity of organic compounds is often determined a by neighboring groups because they can help stabilizing alkane resulting anion i e halogen nitro etc ester their electronegative character or due to resonance aldehyde ketone enolate in carbonyl alcohol for instance presence greatly increases hydrogen atoms protons stabilization ion numbers parentheses below are from acetone am pm many be deprotonated with moderately strong bases hydroxide alcoholates aldol condensation ketones and aldehydes reacted each other claisen schmidt h o oh t ph self acetaldehyde form crotonaldehyde also called formation cinnamaldehyde theory experiment chem cl two equivalents benzaldehyde using sodium as catalyst cho naoh aq etoh ho first step c note that water one products amount has minimized order optimize reaction mixture ii acts nucleophile which attacks new bond trans isomer primarily formed isolated running small erlenmeyer flask an aqueous ethanolic solution added ...