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...Outline where are we up to part hypothesis testing multiple comparisons vs topological inference smoothing random field theory alternatives conclusion spm example hypotheses fmri time series kernel design matrix statistical parametric map motion correction general linear model realign unwarp co registration parameter estimates spatial normalisation standard template test an construct statistics and ask how likely that our statistic could have come about by chance the null h typically what want disprove no effect alternative expresses outcome of interest a t summarises evidence is small in magnitude when true large false need know distribution under one sample se n can estimate using st dev s population estimated mean gives information differences expected due sampling error x for...