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picture1_Design Of Experiments Slideshare 66963 | Scale Up Granulation Updated


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File: Design Of Experiments Slideshare 66963 | Scale Up Granulation Updated
Scale-up Approach with Dimensional Numbers • The effect of process parameter (i.e., impeller speed, liquid addition rate) on the process and thus on granule characteristics are evaluated based on ...

icon picture PPTX Filetype Power Point PPTX | Posted on 28 Aug 2022 | 2 years ago

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...Scale up approach with dimensional numbers the effect of process parameter i e impeller speed liquid addition rate on and thus granule characteristics are evaluated based mechanistic understanding use as variables rather than individual parameters this will decrease number need to be varied experiments includes explicitly implicitly mode determine design space at smallest for given formulation validate larger scales less compared doe mechanical crumb dispersion intermediate f nucleation steady growth p td rapid s drop controlled caking induction a max optimum conditions from duquesne university wet granulation content ml min rpm massing time sec percentage is kept same sensitivity amount tested around level that was obtained small ratio fill height granulator diameter all should constant size l batch kg bowl cm spraying dimensionless spray flux values single nozzle calculated assuming m close too high compare therefore higher amounts lumps expected can lowered by using two nozzles scal...
								

							

						
	
												
				
					
					
					
			
					
				
				
		
	

	
		





	

	
				

						

						
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										Category:  Uncategorized / Uncategorized 
										
Posted on: 28 Aug 2022 | 2 years ago
										
										
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Filetype: PPTX
										
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												Wan learn