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...Sneha jagtap et al j pharm sci res vol solubility enhancement technique a review chandrakant magdum dhanraj jadge rajesh annasaheb dange college of b pharmacy ashta sangli maharashtra india rajarambapu kasegaon abstract is the phenomenon dissolution solid in liquid phase to give homogenous molecular dispersion which essential drug s success but majority active pharmaceutical ingredients are poor aqueous soluble hydrophobic property drugs becomes one most challenging aspects formulation development results important products not reaching finished pharmaceuticals due achieving their full potential and therapeutic range hence major limiting factor with many new successful launch market inspite pharmacokinetic activity molecules that would have highly beneficial effect on physiological target be further developed if bioavailability limited by water also affects physical chemical properties dose stability gastrointestinal track severs as standard for test purity rate extent absorption achie...