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...Methylmalonic acidemia propionic fact sheet this is for educational purposes only an experienced healthcare professional should be consulted the management of or mma and pa protein from energy foods growth what are other amino acids methionine enzyme inherited genetic disorders both caused by defects in enzymes that needed to break down isoleucine threonine made up which important muscles build muscle body tissues normal any valine toxins extra normally broken produce four cannot but instead toxic these significant called propiogenic health problems when someone with either eats too much food does not get enough calories becomes ill blood levels increase so do their byproducts acid present bacteria digestive system also can cause serious life threatening missing working properly methylmalonyl coa mutase it propionyl carboxylase high related many including poor feeding vomiting severe weakness lethargy seizures coma if treated aggressively long term include abnormal movements ataxia lea...