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...July low glycemic index therapy ketogenic diet and supplements as treatments for angelman syndrome jessica duis md ms director dupq clinic childrenscolorado org why consider before kd years following initiation studies have shown that to of patients with dre who use the at least a reduction in seizure frequency months mechanism action efficacy during ketosis there is more efficient synaptic removal glutamate brain s major excitatory neurotransmitter its conversion gamma aminobutyric acid inhibitory via glutamine cycle leads neuronal inhibition acetoacetate bhb inhibit neurotransmission by inhibiting activation vesicular transporters also improves mitochondrial dysfunction associated epileptogenesis types fat carb protein ratio regular lgit treatment g carbohydrates carbs per day modified atkins net all diets are be medically followed doctor dietitian...