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...Efcacyofd cycloserineforenhancingresponseto cognitive behaviortherapyforpanicdisorder michaelw otto davidf tolin naomim simon godfreyd pearlson shawneebasden suzannea meunier stefang hofmann katherineeisenmenger johnh krystal andmarkh pollack background traditional combination strategies of behavior therapy plus pharmacotherapy have met with disappointing results for anxiety disorders enhancement d cycloserine dcs represents a novel strategyforimprovingtherapeuticlearningfromcognitive behaviortherapythatremainsuntestedinpanicdisorder method this is randomized double blind placebo controlled augmentation trial examining the addition isolated doses mg or pill to brief exposure based participants were outpatients meeting dsm ivcriteria panic disorder without agoraphobia who offered ve sessions manualized emphasizing feared internal sensations interoceptive but also including informational and situational interventions study drug administered hour before primary outcomemeasureswerethepanic...