recovery of products definition the isolation and purification of biotechnological product to a form suitable for its intended use culture is harvested at the optimal timing cells are separated from ...
Filetype Power Point PPTX | Posted on 29 Aug 2022 | 4 years ago
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...Recovery of products definition the isolation and purification biotechnological product to a form suitable for its intended use culture is harvested at optimal timing cells are separated from medium downstream processing include whole organic acids amino solvents antibiotics industrial enzymes therapeutic proteins vaccines etc complexity steps determined by required purity which in turn application separation principles also depend on size nature fermentation may be difficult costly costs microbial vary total production cost major problem currently faced large scale biologically active molecules if broth time harvesting it discovered that present low concentration typically g dm an aqueous solution contains intact microorganisms cell fragments soluble insoluble components other metabolic intracellular heat labile easily broken down contaminating all these factors tend increase difficulties ensure good or speed operation factor because choice process based following criteria extracellul...