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circumvention of defective neutral amino acid transport in hartnup disease using tryptophan ethyl ester a j jonas i j butler j clin invest 1989 84 1 200 204 https doi ...

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...Circumvention of defective neutral amino acid transport in hartnup disease using tryptophan ethyl ester a j jonas i butler clin invest https doi org jci research article lipid soluble derivative was used to bypass gastrointestinal child with the s baseline concentrations serum microm and cerebrospinal fluid were persistently less than normal values hydroxyindoleacetic hiaa serotonin metabolite also ng ml increased only modestly briefly after an oral challenge mg kg l reflecting absorptive defect resulted prompt increase peak sustained treatment qh normalization mean more no toxicity observed over mo period chronic diarrhea resolved body weight which had remained unchanged for before therapy by approximately we concluded that is effective at circumventing may be useful find latest version me pdf adam ian harbor ucla medical center torrance california division ofmedical genetics department ofpediatrics texas departments andneurology university oftexas school houston abstract absorption e...

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