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...Brain neurotherapy bio inc balmoral drive oakland ca california institute for regenerative medicine harrison street suite th october re clin a phase b safety study mri guided delivery of aav gdnf the treatment parkinson s disease dear icoc members we are very grateful cirm support our pd clinical testing tolerability and preliminary efficacy delivered to bilateral putamen opportunity provide an update on progress made towards initiation that trial remains second most common human neurodegenerative disorder debilitating illness where neuronal pathway produces neurotransmitter dopamine undergoes exponential degeneration leading disability death based vast preclinical experiences believe gene therapy delivers trophic factor will slow down or even reverse this degenerative process initial in patients with advanced showed over years after data analyses suggesting approach slowed halted progression these mind approached fda were granted permission test higher dose not only but also subjects ...